Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 1/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1693987 | 1.00 | GRN (0.50) | GRNSORT1MAPK1KEAP1PPARA | |
| SCHEMBL1693084 | 1.00 | GRN (0.50) | GRNSORT1MAPK1KEAP1PPARA | |
| Hydrochloric Acid SCHEMBL2490304 | 0.98 | GRN (0.49) | GRNSORT1MAPK1KEAP1PPARA | |
| SCHEMBL19230492 | 0.83 | MAPK1 (0.41) | GRNSORT1MAPK1 | |
| SCHEMBL1361481 | 0.83 | MAPK1 (0.41) | GRNSORT1MAPK1KEAP1BACE1 | |
| SCHEMBL28528204 | 0.83 | MAPK1 (0.41) | GRNSORT1MAPK1KEAP1BACE1 | |
| SCHEMBL19230491 | 0.83 | MAPK1 (0.41) | GRNSORT1MAPK1 | |
| SCHEMBL18515857 | 0.82 | GRN (0.56) | GRNSORT1MAPK1KEAP1PPARA | |
| SCHEMBL978015 | 0.82 | GRN (0.49) | GRNSORT1MAPK1KEAP1PPARA | |
| SCHEMBL13711068 | 0.82 | MAPK1 (0.40) | GRNSORT1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100491345-C | Process for liquid phase synthesis of N-fluorenyl-methoxy-carbonyl-N-methyl-O-tertiary butyl serine | GL BIOCHEM SHANGHAI LTD (CN) | 2009-05-27 | — | — | CN | claimed |
| CN-1837189-A | Process for liquid phase synthesis of N-fluorenyl-methoxy-carbonyl-N-methyl-O-tertiary butyl serine | GL BIOCHEM SHANGHAI LTD (CN) | 2006-09-27 | — | — | CN | claimed |
| US-12624002-B2 | Dimers for use in synthesis of peptidomimetics | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-05-12 | — | — | US | disclosed |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-04-14 | — | — | US | disclosed |
| US-12595233-B2 | Thiosemicarbazates and uses thereof | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2026-04-07 | — | — | US | disclosed |
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2025-07-08 | — | — | US | disclosed |
| WO-2025128985-A1 | SULFOXIDE AND SULFONE DERIVATIVES OF THIOCARBAZATES AS SYNTHONS FOR AZAPEPTIDES SYNTHESIS AND PROCESS OF USING SAME | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2025-06-19 | — | — | WO | disclosed |
| CN-114126619-B | Compounds for the synthesis of peptidomimetics | 范因斯坦医学研究院 | 2024-03-15 | — | — | CN | disclosed |
| EP-3784669-B1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMA (US) | 2023-10-25 | — | — | EP | disclosed |
| US-20230312587-A1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMACEUTICALS INCORPORATED | 2023-10-05 | — | — | US | disclosed |
| US-20230159450-A1 | DIMERS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH | 2023-05-25 | — | — | US | disclosed |
| US-20200354318-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | US | disclosed |
| US-20190322673-A1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMACEUTICALS INCORPORATED | 2019-10-24 | — | — | US | disclosed |
| US-20170267648-A1 | SUBSTITUTED URACILS AS CHYMASE INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-21 | — | — | US | disclosed |
| US-9695131-B2 | Substituted uracils as chymase inhibitors | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-07-04 | — | — | US | disclosed |
| US-20160244415-A1 | SUBSTITUTED URACILS AS CHYMASE INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-08-25 | — | — | US | disclosed |
| EP-2813512-A1 | PEPTIDE-COMPOUND CYCLIZATION METHOD | Chugai Seiyaku Kabushiki Kaisha (JP) | 2014-12-17 | — | — | EP | disclosed |
| US-20090258381-A1 | Methods for Determining the Cleavability of Substrates | FORSCHUNGSZENTRUM BORSTEL (DE) | 2009-10-15 | — | — | US | disclosed |
| US-20090104633-A1 | Kit for Highly Sensitive Detection Assays | VYZKUMNY USTAV VETERINARNIHO LEKARSTVI (CZ) | 2009-04-23 | — | — | US | disclosed |
| US-7368424-B2 | Acylated nonadepsipeptides | AICURIS GMBH & CO. KG (DE) | 2008-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12351573-B2 | Compounds for use in synthesis of peptidomimetics | DNPEP, NPEPPS, PAM | GRN 2407/4885SORT1 2254/4885MAPK1 3722/4885 |
| US-20170267648-A1 | SUBSTITUTED URACILS AS CHYMASE INHIBITORS | CMA1, UNG, TYMP | GRN 1400/4885SORT1 3819/4885MAPK1 4447/4885 |
| US-12624002-B2 | Dimers for use in synthesis of peptidomimetics | GLUL, ARGLU1, ASNS | GRN 852/4885SORT1 4244/4885MAPK1 2531/4885 |
| US-20190322673-A1 | PTERIDINONE COMPOUNDS AND USES THEREOF | DPYD, PKD1, TYMP | GRN 1022/4885SORT1 4248/4885MAPK1 2266/4885 |
| US-12595233-B2 | Thiosemicarbazates and uses thereof | TST, THRB, HSPB1 | GRN 3920/4885SORT1 4138/4885MAPK1 4390/4885 |
| US-20200354318-A1 | THIOSEMICARBAZATES AND USES THEREOF | TST, ABAT, AADAC | GRN 4566/4885SORT1 4083/4885MAPK1 4554/4885 |
| US-20230159450-A1 | DIMERS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS | DNPEP, DAP3, ANPEP | GRN 2393/4885SORT1 1166/4885MAPK1 4070/4885 |
| US-20160244415-A1 | SUBSTITUTED URACILS AS CHYMASE INHIBITORS | UNG, CMA1, TYMP | GRN 1111/4885SORT1 4147/4885MAPK1 3345/4885 |
| US-20090258381-A1 | Methods for Determining the Cleavability of Substrates | CTSF, ADAM17, ADAM10 | GRN 2951/4885SORT1 334/4885MAPK1 4278/4885 |
| US-20230312587-A1 | PTERIDINONE COMPOUNDS AND USES THEREOF | DPYD, PKD1, TYMP | GRN 1022/4885SORT1 4248/4885MAPK1 2266/4885 |
| US-12600699-B2 | Thiosemicarbazates and uses thereof | MET, THRB, ABAT | GRN 3136/4885SORT1 4148/4885MAPK1 4155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.