Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.38 |
| ▸ | FABP1 | P07148 | 7/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230638 | 0.86 | NR1H4 (0.41) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL19230585 | 0.75 | NR1H4 (0.54) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL18843356 | 0.73 | MEN1 (0.40) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL22790299 | 0.70 | NR1H4 (0.42) | NR1H4FABP1 | |
| SCHEMBL12168746 | 0.70 | NR1H4 (0.52) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL23730800 | 0.69 | NR1H4 (0.46) | NR1H4FABP1FABP4 | |
| SCHEMBL12168747 | 0.68 | NR1H4 (0.55) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL12168749 | 0.68 | NR1H4 (0.55) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL22570973 | 0.67 | NR1H4 (0.43) | NR1H4FABP1FABP4 | |
| SCHEMBL21161321 | 0.67 | NR1H4 (0.54) | NR1H4FABP1FABP4HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |