Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 19/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | FABP1 | P07148 | 7/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230639 | 0.86 | NR1H4 (0.38) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL17839774 | 0.81 | NR1H4 (0.47) | NR1H4RETFABP1FABP4 | |
| SCHEMBL1096115 | 0.81 | NR1H4 (0.58) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL20031245 | 0.81 | NR1H4 (0.45) | NR1H4RETFABP1FABP4 | |
| SCHEMBL19690334 | 0.77 | NR1H4 (0.43) | NR1H4RETFABP1FABP4HSD17B13 | |
| SCHEMBL17839653 | 0.77 | RET (0.42) | NR1H4RETFABP1FABP4HSD17B13 | |
| SCHEMBL19899990 | 0.76 | NR1H4 (0.49) | NR1H4RETFABP1FABP4 | |
| SCHEMBL2006099 | 0.76 | NR1H4 (0.53) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL2003900 | 0.76 | NR1H4 (0.53) | NR1H4FABP1FABP4HSD17B13 | |
| SCHEMBL23906961 | 0.76 | NOTUM (0.45) | NR1H4RETFABP1FABP4HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |