Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 6/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11637870 | 0.95 | ACLY (0.56) | ACLYNAAA | |
| SCHEMBL1404936 | 0.91 | PDPK1 (0.54) | ACLYPDPK1GAAPLAAT3PLAAT5 | |
| SCHEMBL30799277 | 0.91 | PDPK1 (0.54) | ACLYPDPK1GAAPLAAT3PLAAT5 | |
| SCHEMBL27454018 | 0.85 | ACLY (0.59) | ACLYNAAAPDPK1PLAAT3PLAAT5 | |
| SCHEMBL4778926 | 0.84 | ACLY (0.58) | ACLYPDPK1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL9083835 | 0.84 | ACLY (0.51) | ACLYNAAAPDPK1PLAAT3PLAAT5 | |
| Hydrochloric Acid SCHEMBL9083841 | 0.82 | ACLY (0.57) | ACLYPDPK1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL6207183 | 0.81 | ACLY (0.63) | ACLYNAAA | |
| SCHEMBL10900027 | 0.81 | ACLY (0.56) | ACLYNAAAPDPK1PLAAT3PLAAT5 | |
| SCHEMBL29712851 | 0.79 | IDO1 (0.50) | GAAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603029-A | Synthesis method of penconazole key intermediate | 江苏禾本生化有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-117603029-A | Synthesis method of penconazole key intermediate | 江苏禾本生化有限公司 | 2024-02-27 | — | — | CN | disclosed |
| EP-2328902-A1 | PYRAZOLO [5,1-B]OXAZOLE DERIVATIVES AS CRF1 ANTAGONISTS | Novartis AG (CH) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010015628-A1 | PYRAZOLO [5,1-B] OXAZOLE DERIVATIVES AS CRF1 ANTAGONISTS | NOVARTIS AG (CH) | 2010-02-11 | — | — | WO | disclosed |
| EP-0636120-A1 | EPOXIDATION PROCESS OF CARBONYL COMPOUNDS USING SULPHONIUM OR SULPHOXONIUM YLIDES AND INTERMEDIATES | ZENECA LIMITED (GB) | 1995-02-01 | — | — | EP | disclosed |
| WO-1992014703-A1 | EPOXIDATION PROCESS OF CARBONYL COMPOUNDS USING SULPHONIUM OR SULPHOXONIUM YLIDES AND INTERMEDIATES | ZENECA LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |