Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC8A1 | P32418 | 19/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230606 | 0.89 | ESR1 (0.38) | SLC8A1ESR1ESR2 | |
| SCHEMBL19230537 | 0.87 | SLC8A1 (0.36) | SLC8A1 | |
| SCHEMBL19230551 | 0.84 | SLC8A1 (0.31) | SLC8A1 | |
| SCHEMBL19230654 | 0.83 | ITGB3 (0.33) | SLC8A1 | |
| SCHEMBL19230563 | 0.80 | SLC8A1 (0.32) | SLC8A1 | |
| SCHEMBL19230634 | 0.79 | NR1H4 (0.37) | SLC8A1 | |
| SCHEMBL19230520 | 0.77 | PPARG (0.33) | ESR1ESR2 | |
| SCHEMBL19230764 | 0.75 | SLC8A1 (0.40) | SLC8A1 | |
| SCHEMBL18397064 | 0.74 | CSF1R (0.46) | SLC8A1ESR1ESR2 | |
| SCHEMBL29858881 | 0.74 | CSF1R (0.46) | SLC8A1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |