Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.54 |
| ▸ | FXR2 | P51116 | 1/20 | 0.54 |
| ▸ | FABP1 | P07148 | 4/20 | 0.51 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230765 | 0.88 | NR1H4 (0.56) | NR1H4FXR2FABP1HSD17B13 | |
| SCHEMBL19230580 | 0.87 | NR1H4 (0.68) | NR1H4FXR2HSD17B13 | |
| SCHEMBL19230814 | 0.87 | NR1H4 (0.56) | NR1H4FXR2FABP1 | |
| SCHEMBL19230581 | 0.85 | NR1H4 (0.58) | NR1H4FXR2 | |
| SCHEMBL28835403 | 0.81 | NR1H4 (0.64) | NR1H4FXR2FABP1HSD17B13FABP4 | |
| SCHEMBL29904882 | 0.81 | NR1H4 (0.64) | NR1H4FXR2FABP1HSD17B13FABP4 | |
| SCHEMBL19230579 | 0.81 | NR1H4 (0.54) | NR1H4FXR2 | |
| SCHEMBL18724891 | 0.81 | NR1H4 (0.71) | NR1H4FXR2 | |
| SCHEMBL19230792 | 0.80 | NR1H4 (0.58) | NR1H4FXR2FABP1 | |
| SCHEMBL29904908 | 0.79 | NR1H4 (0.68) | NR1H4FXR2FABP1HSD17B13FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |