Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.55 |
| ▸ | FABP1 | P07148 | 3/20 | 0.53 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230963 | 0.95 | NR1H4 (0.53) | NR1H4FABP1 | |
| SCHEMBL19230632 | 0.87 | NR1H4 (0.69) | NR1H4HSD17B13 | |
| SCHEMBL19230653 | 0.85 | NR1H4 (0.58) | NR1H4HSD17B13 | |
| SCHEMBL19230792 | 0.83 | NR1H4 (0.58) | NR1H4FABP1 | |
| SCHEMBL19230630 | 0.82 | NR1H4 (0.69) | NR1H4HSD17B13 | |
| SCHEMBL19230627 | 0.82 | NR1H4 (0.69) | NR1H4HSD17B13 | |
| SCHEMBL19230814 | 0.80 | NR1H4 (0.56) | NR1H4FABP1 | |
| SCHEMBL12168836 | 0.80 | NR1H4 (0.68) | NR1H4FABP1HSD17B13 | |
| SCHEMBL29904908 | 0.80 | NR1H4 (0.68) | NR1H4FABP1HSD17B13 | |
| SCHEMBL19230964 | 0.80 | NR1H4 (0.53) | NR1H4FABP1HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |