Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC8A1 | P32418 | 11/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230563 | 0.87 | SLC8A1 (0.32) | PPARGPPARDPPARAKDM4EALDH1A1 | |
| SCHEMBL19230546 | 0.79 | SLC8A1 (0.34) | PPARDSLC8A1 | |
| SCHEMBL19230558 | 0.79 | NR1H4 (0.40) | SLC8A1 | |
| SCHEMBL19230654 | 0.78 | ITGB3 (0.33) | SLC8A1 | |
| SCHEMBL19230809 | 0.76 | NR1H4 (0.35) | SLC8A1 | |
| SCHEMBL19230560 | 0.76 | NR1H4 (0.37) | PPARGPPARDPPARASLC8A1 | |
| SCHEMBL19230780 | 0.75 | SLC8A1 (0.33) | SLC8A1 | |
| SCHEMBL19230606 | 0.73 | ESR1 (0.38) | SLC8A1 | |
| SCHEMBL19230551 | 0.73 | SLC8A1 (0.31) | SLC8A1 | |
| SCHEMBL19230975 | 0.72 | PPARG (0.36) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |