Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.45 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19403504 | 0.93 | SSTR3 (0.54) | SSTR3MMP3CALCRLECE1LTA4H | |
| SCHEMBL25475432 | 0.93 | SSTR3 (0.54) | SSTR3MMP3CALCRLECE1LTA4H | |
| SCHEMBL21474554 | 0.91 | SSTR3 (0.55) | SSTR3MMP3CALCRLECE1LTA4H | |
| SCHEMBL14872058 | 0.91 | SSTR3 (0.55) | SSTR3MMP3CALCRLECE1LTA4H | |
| SCHEMBL22010347 | 0.88 | SSTR3 (0.51) | SSTR3MMP3CALCRLECE1LTA4H | |
| SCHEMBL25475433 | 0.86 | SSTR3 (0.48) | SSTR3MMP3CALCRLECE1LTA4H | |
| SCHEMBL25475437 | 0.85 | FOLH1 (0.48) | SSTR3MMP3CALCRLECE1F2 | |
| SCHEMBL25475918 | 0.85 | SSTR3 (0.48) | SSTR3MMP3CALCRLECE1LTA4H | |
| SCHEMBL17706674 | 0.83 | SSTR3 (0.55) | SSTR3MMP3CALCRLECE1LTA4H | |
| SCHEMBL14821040 | 0.83 | SSTR3 (0.55) | SSTR3MMP3CALCRLECE1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732084-B2 | Pyrrolobenzodiazepines used to treat proliferative diseases | MEDIMMUNE LIMITED (GB) | 2017-08-15 | — | — | US | disclosed |