Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 9/20 | 0.60 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.42 |
| ▸ | GPR6 | P46095 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781805 | 0.94 | SCD (0.49) | SCDFPR2PROKR1GPR6 | |
| SCHEMBL1782817 | 0.94 | SCD (0.67) | SCDPDE10A | |
| SCHEMBL1784148 | 0.87 | SCD (0.67) | SCD | |
| SCHEMBL1783508 | 0.81 | SCD (0.64) | SCDPDE10A | |
| SCHEMBL1784138 | 0.81 | SCD (0.50) | SCDFPR2PROKR1PDE10A | |
| SCHEMBL1779895 | 0.80 | SCD (0.67) | SCD | |
| SCHEMBL1780589 | 0.80 | SCD (0.69) | SCDFPR2PROKR1 | |
| SCHEMBL1782516 | 0.80 | SCD (0.58) | SCDPDE10A | |
| SCHEMBL1782040 | 0.79 | FPR2 (0.49) | SCDFPR2PROKR1 | |
| SCHEMBL1784632 | 0.79 | SCD (0.54) | SCDGPR6PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011528007-A | — | — | 2011-11-10 | — | — | JP | claimed |
| EP-2328886-A1 | DERIVATIVES OF TRIAZINES AND URACILS, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPEUTICS | Pierre Fabre Médicament (FR) | 2011-06-08 | — | — | EP | claimed |
| WO-2010006962-A1 | DERIVATIVES OF TRIAZINES AND URACILS, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2010-01-21 | — | — | WO | claimed |
| EP-2328886-A1 | DERIVATIVES OF TRIAZINES AND URACILS, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPEUTICS | Pierre Fabre Médicament (FR) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010006962-A1 | DERIVATIVES OF TRIAZINES AND URACILS, THEIR PREPARATION AND THEIR APPLICATION IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2010-01-21 | — | — | WO | disclosed |