SCHEMBL1923201

SCHEMBL1923201

FC(F)(F)Oc1ccc(Nc2ccc(Nc3ccc(OC(F)(F)F)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.61
EPHX2 P34913 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.53
KDM4E B2RXH2 2/20 0.53
KIF11 P52732 1/20 0.52
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
KCNH2 Q12809 2/20 0.50
SCN5A Q14524 2/20 0.50
SCN9A Q15858 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
TTBK1 Q5TCY1 1/20 0.50
TTBK2 Q6IQ55 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3194551 1.00 MAPT (0.61) MAPTEPHX2L3MBTL1KDM4EKIF11
SCHEMBL1921523 0.93 KIF11 (0.61) MAPTEPHX2L3MBTL1KDM4EKIF11
SCHEMBL11125111 0.91 CTSC (0.56) MAPTEPHX2L3MBTL1KDM4EKIF11
SCHEMBL9070626 0.89 MAPT (0.52) MAPTEPHX2L3MBTL1KDM4EKIF11
SCHEMBL9073469 0.89 MAPT (0.68) MAPTEPHX2L3MBTL1KDM4EKIF11
SCHEMBL15146260 0.89 MAPT (0.56) MAPTEPHX2L3MBTL1KDM4EKIF11
SCHEMBL5543407 0.88 MAPT (0.50) MAPTEPHX2L3MBTL1KDM4EKIF11
SCHEMBL31212780 0.85 MAPT (0.61) MAPTEPHX2L3MBTL1KDM4EKIF11
SCHEMBL31212781 0.85 MAPT (0.61) MAPTEPHX2L3MBTL1KDM4EKIF11
SCHEMBL1923203 0.85 MAPT (0.53) MAPTEPHX2L3MBTL1KDM4EKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed