SCHEMBL19234875

SCHEMBL19234875

c1ccc2c(-c3cccc4c3oc3ccccc34)nc(-n3c4ccccc4c4cc5c(cc43)c3ccccc3sc3ccccc3c3ccccc35)nc2c1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.33
PRKDC P78527 2/20 0.32
PIK3CD O00329 1/20 0.32
PIK3CB P42338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19234968 0.86 ALOX5 (0.33) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL21213731 0.85 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL19234883 0.85 ALOX5 (0.34) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL19239335 0.84
SCHEMBL24802736 0.84
SCHEMBL18962024 0.83 ALOX5 (0.33) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL18962018 0.83 ALOX5 (0.33) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL23026789 0.83 ALOX5 (0.34) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL14756493 0.83 ALOX5 (0.32) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL21161561 0.82 ALOX5 (0.36) ALOX5PRKDCPIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732099-B1 Organic electroluminescent compounds and organic electroluminescent devices comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-08-15 US disclosed