Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | ACR | P10323 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1923594 | 0.86 | PRSS1 (0.68) | PRSS1ACRKMT2APPARAMAPT | |
| SCHEMBL14130431 | 0.83 | MAPT (0.58) | PRSS1ACRKMT2AMAPTLMNA | |
| SCHEMBL3344394 | 0.80 | PRSS1 (0.49) | PRSS1ACRKMT2AMAPTLMNA | |
| SCHEMBL30279573 | 0.79 | CYP1A2 (0.50) | KMT2APPARAMAPTLMNANPC1 | |
| SCHEMBL5706230 | 0.78 | KMT2A (0.70) | PRSS1ACRKMT2AMAPTLMNA | |
| SCHEMBL14130187 | 0.78 | SERPINE1 (0.47) | PRSS1ACRKMT2AMAPTNPC1 | |
| SCHEMBL10596404 | 0.77 | NPC1 (0.61) | KMT2AMAPTLMNANPC1CYP1A2 | |
| SCHEMBL9152639 | 0.77 | NPC1 (0.61) | KMT2AMAPTLMNANPC1CYP1A2 | |
| SCHEMBL5705976 | 0.77 | KMT2A (0.55) | PRSS1ACRKMT2APPARAMAPT | |
| SCHEMBL26602060 | 0.77 | PRSS1 (0.70) | PRSS1ACRKMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328541-A1 | A STIMULATABLE ASYMMETRICAL POLYMERSOME | Institut Curie (FR) | 2011-06-08 | — | — | EP | claimed |