Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.68 |
| ▸ | ACR | P10323 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.56 |
| ▸ | RELA | Q04206 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26602060 | 0.90 | PRSS1 (0.70) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL5706230 | 0.89 | KMT2A (0.70) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL30030754 | 0.87 | LMNA (0.69) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL1923591 | 0.86 | PRSS1 (0.52) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL9829760 | 0.86 | NPC1 (0.72) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL19930172 | 0.86 | PRSS1 (0.64) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL14130027 | 0.85 | MAPT (0.66) | PRSS1ACRKMT2AMAPTRAB9A | |
| SCHEMBL11646532 | 0.85 | LMNA (0.74) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL27740551 | 0.85 | LMNA (0.74) | PRSS1ACRLMNANPC1CYP1A2 | |
| SCHEMBL27279499 | 0.85 | MAPT (0.66) | PRSS1ACRKMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328541-A1 | A STIMULATABLE ASYMMETRICAL POLYMERSOME | Institut Curie (FR) | 2011-06-08 | — | — | EP | claimed |