Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | HTR1A | P08908 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | GRK2 | P25098 | 2/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.65 |
| ▸ | MPO | P05164 | 1/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.65 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.65 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30589885 | 1.00 | L3MBTL1 (0.70) | L3MBTL1CYP3A4HTR1ATP53CYP1A2 | |
| SCHEMBL7957720 | 1.00 | L3MBTL1 (0.70) | L3MBTL1CYP3A4HTR1ATP53CYP1A2 | |
| SCHEMBL9526894 | 1.00 | L3MBTL1 (0.70) | L3MBTL1CYP3A4HTR1ATP53CYP1A2 | |
| SCHEMBL3073046 | 0.92 | L3MBTL1 (0.61) | L3MBTL1CYP3A4HTR1ATP53CYP1A2 | |
| SCHEMBL12538358 | 0.92 | L3MBTL1 (0.61) | L3MBTL1CYP3A4HTR1ATP53CYP1A2 | |
| SCHEMBL8601438 | 0.91 | L3MBTL1 (0.58) | L3MBTL1CYP3A4HTR1ATP53CYP1A2 | |
| SCHEMBL8601442 | 0.91 | L3MBTL1 (0.58) | L3MBTL1CYP3A4HTR1ATP53CYP1A2 | |
| SCHEMBL7966834 | 0.90 | L3MBTL1 (0.58) | L3MBTL1CYP3A4HTR1ATP53CYP1A2 | |
| SCHEMBL5083142 | 0.88 | L3MBTL1 (0.66) | L3MBTL1CYP3A4HTR1ATP53CYP1A2 | |
| SCHEMBL5083143 | 0.88 | L3MBTL1 (0.66) | L3MBTL1CYP3A4HTR1ATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133517-A1 | PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF | 四川海思科制药有限公司 | 2017-08-10 | — | — | WO | disclosed |