SCHEMBL19236428

CC(C)(C)OC(=O)N[C@H]1CCCCC/C=C\[C@@H]2C[C@@]2(C(N)=O)NC(=O)[C@@H]2CC(OC(=O)N3Cc4cccc(F)c4C3)CN2C1=O

nearest known ligand 0.48

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	ADRB3	P13945	1/20	0.39

▸	ADRA2B	P18089	1/20	0.39

▸	ADRA2C	P18825	1/20	0.39

▸	CYP3A4	P08684	2/20	0.35

▸	DDB1	Q16531	1/20	0.33

▸	CRBN	Q96SW2	1/20	0.33

▸	PDE4B	Q07343	2/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11983993	1.00	ADRB3 (0.39)	ADRB3ADRA2BADRA2CCYP3A4DDB1
SCHEMBL8277037	0.95	ADRB3 (0.39)	ADRB3ADRA2BADRA2CCYP3A4DDB1
SCHEMBL17970111	0.95	ADRB3 (0.44)	ADRB3ADRA2BADRA2CCYP3A4DDB1
SCHEMBL3369231	0.95	ADRB3 (0.41)	ADRB3ADRA2BADRA2CCYP3A4DDB1
SCHEMBL498005	0.95	ADRB3 (0.44)	ADRB3ADRA2BADRA2CCYP3A4DDB1
SCHEMBL498004	0.95	ADRB3 (0.44)	ADRB3ADRA2BADRA2CCYP3A4DDB1
SCHEMBL8161544	0.95	ADRB3 (0.44)	ADRB3ADRA2BADRA2CCYP3A4DDB1
SCHEMBL3970772	0.95	ADRB3 (0.44)	ADRB3ADRA2BADRA2CCYP3A4DDB1
SCHEMBL3369227	0.95	ADRB3 (0.41)	ADRB3ADRA2BADRA2CCYP3A4DDB1
SCHEMBL8160007	0.95	ADRB3 (0.41)	ADRB3ADRA2BADRA2CCYP3A4DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2017133517-A1	PHOSPHAMIDE DERIVATIVE, METHOD FOR MANUFACTURING THE SAME, AND USES THEREOF	四川海思科制药有限公司	2017-08-10	—	—	WO	disclosed