Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966158 | 0.85 | EPHX1 (0.45) | EPHX1HTTNAAACYP19A1CYP2C19 | |
| SCHEMBL7371640 | 0.80 | EPHX1 (0.39) | EPHX1HTTNAAACYP19A1CYP2C19 | |
| SCHEMBL13130088 | 0.80 | EPHX1 (0.41) | EPHX1HTTNAAACYP19A1CYP2C19 | |
| SCHEMBL7606345 | 0.78 | EPHX1 (0.40) | EPHX1HTTNAAACYP19A1CYP2C19 | |
| SCHEMBL5987477 | 0.78 | EPHX1 (0.40) | EPHX1HTTNAAACYP19A1CYP2C19 | |
| SCHEMBL23222733 | 0.78 | EPHX1 (0.40) | EPHX1HTTNAAACYP19A1CYP2C19 | |
| SCHEMBL16805821 | 0.78 | EPHX1 (0.40) | EPHX1HTTNAAACYP19A1CYP2C19 | |
| SCHEMBL5986431 | 0.78 | EPHX1 (0.40) | EPHX1HTTNAAACYP19A1CYP2C19 | |
| SCHEMBL13662184 | 0.78 | NAAA (0.46) | EPHX1HTTNAAACYP19A1CYP2C19 | |
| SCHEMBL20388745 | 0.78 | EPHX1 (0.42) | EPHX1HTTNAAACYP19A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714648-B1 | NEPRILYSIN INHIBITORS | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2017-08-16 | — | — | EP | disclosed |