⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13268506 | 1.00 | — | — | |
| SCHEMBL13268513 | 1.00 | — | — | |
| SCHEMBL2846868 | 0.86 | ALDH1A1 (0.48) | — | |
| SCHEMBL667964 | 0.82 | — | — | |
| SCHEMBL26198968 | 0.80 | — | — | |
| SCHEMBL18478347 | 0.80 | — | — | |
| SCHEMBL6636082 | 0.80 | — | — | |
| SCHEMBL8370879 | 0.79 | — | — | |
| SCHEMBL22412962 | 0.79 | CYP2D6 (0.40) | — | |
| SCHEMBL1317007 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794203-B1 | FUNCTIONAL ADDITION POLYMERS AND A METHOD FOR THEIR PREPARATION | BASF CORP (US) | 2011-06-08 | — | — | EP | claimed |
| US-20240132517-A1 | MACROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | GOHARMONY THERAPEUTICS (SHENZHEN) CO., LTD. (CN) | 2024-04-25 | — | — | US | disclosed |
| WO-2024008941-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2024-01-11 | — | — | WO | disclosed |
| CN-110950889-B | Multi-target kinase inhibitor and preparation method and application thereof | 北京赛林泰医药技术有限公司 | 2022-04-05 | — | — | CN | disclosed |
| EP-3877356-A1 | BICYCLIC COMPOUNDS | Vivace Therapeutics, Inc. (US) | 2021-09-15 | — | — | EP | disclosed |
| US-10859585-B2 | Lipid probes and uses thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-08 | — | — | US | disclosed |
| CN-107434803-B | Inhibitors of histone demethylases | 吉利德科学公司 | 2020-05-05 | — | — | CN | disclosed |
| CN-110950889-A | Multi-target kinase inhibitor and preparation method and application thereof | 北京赛林泰医药技术有限公司 | 2020-04-03 | — | — | CN | disclosed |
| US-20190293666-A1 | LIPID PROBES AND USES THEREOF | SCRIPPS RESEARCH INST (US) | 2019-09-26 | — | — | US | disclosed |
| US-10377748-B2 | Hepatitis B core protein modulators | ASSEMBLY BIOSCIENCES, INC. (US) | 2019-08-13 | — | — | US | disclosed |
| US-20130109679-A1 | HETEROCYCLIC COMPOUNDS CONTAINING AN INDOLE CORE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-05-02 | — | — | US | disclosed |
| EP-2509980-A1 | HETEROCYCLIC COMPOUNDS CONTAINING AN INDOLE CORE | Boehringer Ingelheim International GmbH (DE) | 2012-10-17 | — | — | EP | disclosed |
| EP-2509979-A1 | HETEROCYCLIC COMPOUNDS CONTAINING A PYRROLOPYRIDINE OR BENZIMIDAZOLE CORE | Boehringer Ingelheim International GmbH (DE) | 2012-10-17 | — | — | EP | disclosed |
| CN-102414168-A | Bridged spiro [2.4] heptane derivatives as ALX receptor and/or FPRL2 agonists | ACTELION PHARMACEUTICALS LTD | 2012-04-11 | — | — | CN | disclosed |
| WO-2011071725-A1 | HETEROCYCLIC COMPOUNDS CONTAINING A PYRROLOPYRIDINE OR BENZIMIDAZOLE CORE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-06-16 | — | — | WO | disclosed |
| US-6710203-B2 | REACTING AQUEOUS AMMONIUM HYDROXIDE AND A CYCLIC CARBONATE TO OBTAIN HYDROXYALKYLCARBAMATE | HUNTSMAN PETROCHEMICAL CORPORATION | 2004-03-23 | — | — | US | disclosed |
| EP-1320519-A1 | PREPARATION OF HYDROXYALKYLCARBAMATES FROM SIX-MEMBERED CYCLIC CARBONATES | HUNTSMAN PETROCHEMICAL CORPORATION (US) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002026700-A1 | PREPARATION OF HYDROXYALKYLCARBAMATES FROM SIX-MEMBERED CYCLIC CARBONATES | HUNTSMAN PETROCHEMICAL CORPORATION (US) | 2002-04-04 | — | — | WO | disclosed |
| US-20020040160-A1 | Preparation of hydroxyalkylcarbamates from six-membered cyclic carbonates | HUNTSMAN PETROCHEMICAL CORPORATION (N/K/A HUNTSMAN PETROCHEMICAL LLC) | 2002-04-04 | — | — | US | disclosed |
| US-6262297-B1 | DECYCLIZATION USING AMMONIA | HUNTSMAN PETROCHEMICAL CORPORATION | 2001-07-17 | — | — | US | disclosed |