SCHEMBL1923916

SCHEMBL1923916

Fc1ccc(Nc2nc(NCc3ccnc(F)c3)nc(Nc3ccc(F)cc3)n2)cc1

nearest known ligand 0.97

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 20/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3413936 0.99 KCNH3 (1.00) KCNH3
SCHEMBL1281719 0.95 KCNH3 (0.97) KCNH3
SCHEMBL1923404 0.94 KCNH3 (0.98) KCNH3
Hydrochloric Acid SCHEMBL541197 0.94 KCNH3 (1.00) KCNH3
SCHEMBL1924293 0.94 KCNH3 (0.98) KCNH3
Hydrochloric Acid SCHEMBL3410329 0.92 KCNH3 (1.00) KCNH3
Hydrochloric Acid SCHEMBL3413499 0.92 KCNH3 (1.00) KCNH3
SCHEMBL1923730 0.90 KCNH3 (0.98) KCNH3
Hydrochloric Acid SCHEMBL3411999 0.89 KCNH3 (1.00) KCNH3
SCHEMBL1923802 0.89 KCNH3 (0.88) KCNH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1479397-B1 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE ASTELLAS PHARMA INC (JP) 2011-06-08 EP claimed
US-7375222-B2 2,4,6-Triamino-1,3,5-triazine derivative ASTELLAS PHARMA INC. (JP) 2008-05-20 US claimed