Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19239369 | 0.99 | KDM4E (0.36) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL19239351 | 0.99 | KDM4E (0.36) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL19239360 | 0.97 | KDM4E (0.35) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL19239361 | 0.97 | KDM4E (0.35) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL26287293 | 0.97 | KDM4E (0.36) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL19239368 | 0.97 | KDM4E (0.39) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL22267441 | 0.96 | KDM4E (0.34) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL20821854 | 0.96 | KDM4E (0.34) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL26287291 | 0.96 | KDM4E (0.35) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL24701655 | 0.96 | KDM4E (0.38) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9876181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-01-23 | — | — | US | disclosed |
| US-9876181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-01-23 | — | — | US | disclosed |
| US-20170237017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
| US-20170237017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170237017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, ETFA, TST | KDM4E 1629/4885ATM 4129/4885L3MBTL1 1145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.