Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | LTK | P29376 | 1/20 | 0.30 |
| ▸ | GRK5 | P34947 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4973748 | 0.83 | CRBN (0.47) | CRBNOR51E2GAAFKBP5 | |
| Diketopiperazine SCHEMBL27918928 | 0.83 | CRBN (0.47) | CRBNOR51E2GAAFKBP5 | |
| SCHEMBL31296913 | 0.83 | CRBN (0.47) | CRBNOR51E2GAAFKBP5 | |
| SCHEMBL24827100 | 0.83 | CRBN (0.47) | CRBNOR51E2GAAFKBP5 | |
| Diketopiperazine SCHEMBL66638 | 0.83 | — | — | |
| SCHEMBL23975525 | 0.83 | CRBN (0.47) | CRBNOR51E2GAAFKBP5 | |
| SCHEMBL21785045 | 0.83 | CRBN (0.47) | CRBNOR51E2GAAFKBP5CHEK1 | |
| SCHEMBL31059 | 0.83 | — | — | |
| SCHEMBL9058472 | 0.83 | CRBN (0.47) | CRBNOR51E2GAAFKBP5CHEK1 | |
| SCHEMBL2672858 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021360-B1 | CYCLODIPEPTIDE SYNTHETASE AND ITS USE FOR SYNTHESIS OF CYCLO(TYR-Xaa) CYCLODIPEPTIDES | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2011-09-14 | — | — | EP | disclosed |
| EP-2021357-B1 | CYCLODIPEPTIDE SYNTHETASES AND THEIR USE FOR SYNTHESIS OF CYCLO(LEU-LEU) CYCLODIPEPTIDE | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2011-06-08 | — | — | EP | disclosed |