Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.31 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.31 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881391 | 0.87 | ADORA2A (0.35) | ADORA2ATMPRSS2PI4KAPI4K2BPI4K2A | |
| SCHEMBL881455 | 0.86 | ADORA2A (0.37) | ADORA2ATMPRSS2PI4KAPI4K2BPI4K2A | |
| SCHEMBL14996141 | 0.86 | ADORA2A (0.37) | ADORA2ATMPRSS2PI4KAPI4K2BPI4K2A | |
| SCHEMBL881677 | 0.83 | TMPRSS2 (0.40) | ADORA2ATMPRSS2PI4KAPI4K2BPI4K2A | |
| SCHEMBL881450 | 0.83 | ADORA2A (0.33) | ADORA2ATMPRSS2PI4KAPI4K2BPI4K2A | |
| SCHEMBL19242542 | 0.83 | ADORA2A (0.34) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL16519851 | 0.81 | ADORA2A (0.38) | ADORA2ATMPRSS2PI4KAPI4K2BPI4K2A | |
| SCHEMBL12243240 | 0.81 | ADORA2A (0.38) | ADORA2ATMPRSS2PI4KAPI4K2BPI4K2A | |
| SCHEMBL12243128 | 0.79 | ADORA2A (0.38) | ADORA2ATMPRSS2PI4KAPI4K2BPI4K2A | |
| SCHEMBL12393219 | 0.79 | ADORA2A (0.38) | ADORA2ATMPRSS2PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2752422-B1 | Stereoselective synthesis of phosphorus containing actives | GILEAD PHARMASSET LLC (US) | 2017-08-16 | — | — | EP | disclosed |