SCHEMBL19244

SCHEMBL19244

O=[N+]([O-])c1cccc2onnc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
MAPT P10636 2/20 0.46
GAA P10253 1/20 0.46
PDE10A Q9Y233 1/20 0.46
TXNRD1 Q16881 1/20 0.45
TXNRD3 Q86VQ6 1/20 0.45
TXNRD2 Q9NNW7 1/20 0.45
TDP1 Q9NUW8 3/20 0.44
GPR35 Q9HC97 2/20 0.42
ALDH1A1 P00352 3/20 0.41
TSHR P16473 3/20 0.41
KDM4E B2RXH2 2/20 0.41
NOS1 P29475 2/20 0.41
NOS2 P35228 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29732491 1.00 MEN1 (0.46) MEN1KMT2AMAPTGAAPDE10A
Fluoride SCHEMBL10627364 0.98 MEN1 (0.45) MEN1KMT2AMAPTGAAPDE10A
Hydrochloric Acid SCHEMBL10625153 0.98 MEN1 (0.45) MEN1KMT2AMAPTGAAPDE10A
SCHEMBL1100716 0.94 MEN1 (0.42) MEN1KMT2AMAPTGAAPDE10A
SCHEMBL1100717 0.91 MEN1 (0.40) MEN1KMT2AMAPTGAAPDE10A
Piperazine SCHEMBL28829870 0.91 MEN1 (0.40) MEN1KMT2AMAPTGAAPDE10A
SCHEMBL15941573 0.91 TXNRD1 (0.45) MEN1KMT2AMAPTGAAPDE10A
Iodoacetamide SCHEMBL8013117 0.86 MAPT (0.40) MEN1KMT2AMAPTGAAPDE10A
Alanine SCHEMBL10613024 0.85 MEN1 (0.39) MEN1KMT2AMAPTGAAPDE10A
Alanine SCHEMBL10613029 0.85 MEN1 (0.39) MEN1KMT2AMAPTGAAPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2989 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12616656-B2 Adventitial painting modality of local drug delivery to abate intimal hyperplasia UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2026-05-05 US claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-12584916-B2 Method for measuring the modulation of the activation of a G protein-coupled receptor with GTP analogues CISBIO BIOASSAYS (FR) 2026-03-24 US claimed
US-12522656-B2 Anti-G-protein alpha antibody CISBIO BIOASSAYS (FR) 2026-01-13 US claimed
WO-2025245370-A1 FLUORESCENCE-BASED DETECTION METHODS, COMPOUND PANELS, AND ARRAYS INCLUDING THE SAME FOR FLUORESCENCE DETECTION ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2025-11-27 WO claimed
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4624903-A1 LIQUID SPRAY ANALYSIS Rolls-Royce plc (GB) 2025-10-01 EP claimed
US-20250297956-A1 LIQUID SPRAY ANALYSIS ROLLS-ROYCE PLC (GB) 2025-09-25 US claimed
US-12292451-B2 ApoA1 exchange rate assays in serum CLEVELAND CLINIC FOUNDATION (US) 2025-05-06 US claimed
EP-1498105-A2 Composition containing at least one conductive polymer and non-film forming rigid particles, corresponding process and use L'OREAL (FR) 2005-01-19 EP claimed
EP-1498106-A2 Composition containing a conductive polymer and at least one film-forming polymer, corresponding process and use L'OREAL (FR) 2005-01-19 EP claimed
EP-1498110-A1 Composition comprising a conducting polymer and an optical brightener and/or a fluorescent compound L'OREAL (FR) 2005-01-19 EP claimed
WO-2003093287-A1 NOVEL METHOD FOR PREPARING ALPHA-GLYCOSYLCERAMIDES, NOVEL ALPHA-GLYCOSYLCERAMIDE DERIVATIVES AND THEIR USES INSTITUT PASTEUR (FR) 2003-11-13 WO claimed
US-6596544-B1 Diagnosing atherosclerosis in mammals; obtain tissue sample, incbae with oxidized phospholipid, monitor adjustment in oxidation of phospholipid, absence of adjustment indicates atherosclerosis THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-07-22 US claimed
US-6495687-B1 ADENOSINE RECEPTORS ARE INVOLVED IN A VAST NUMBER OF PERIPHERAL AND CENTRAL REGULATORY MECHANISMS SUCH AS, FOR EXAMPLE, VASODILATION, CARDIAC DEPRESSION, INHIBITION OF LIPOLYSIS, INHIBITION OF INSULIN RELEASE AND POTENTIATION ENDACEA, INC. 2002-12-17 US claimed
US-5777133-A Synthesis of 1, 2-dioxetanes and intermediates therefor TROPIX, INC. (US) 1998-07-07 US claimed
US-5364764-A Immunoassay of HIV MOLECULAR PROBES, INC. (US) 1994-11-15 US claimed
US-5248770-A Labels such as fluorescent or radioactive compounds THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1993-09-28 US claimed
US-4537718-A GLUTATHIONE JOINED BY LINKAGE GROUPS TO A SECTROSCOPIC REPORTER COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1985-08-27 US claimed