Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.30 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519699 | 0.89 | PDE5A (0.34) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL19244701 | 0.86 | PTGDR2 (0.40) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL19244698 | 0.86 | GRIN1 (0.34) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL19244706 | 0.84 | GRIN1 (0.34) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL15519721 | 0.84 | PTGDR2 (0.39) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL175275 | 0.84 | PDE5A (0.47) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL19244708 | 0.82 | PDE5A (0.36) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL14746418 | 0.82 | PDE5A (0.41) | PDE5AGUCY1A1GUCY1B1 | |
| Acetic Acid SCHEMBL15937793 | 0.81 | PDE5A (0.33) | PDE5AGUCY1A1GUCY1B1 | |
| SCHEMBL15944483 | 0.80 | PDE5A (0.30) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729476-B1 | HETEROARYL SUBSTITUTED PYRAZOLOPYRIDINES AND THEIR USE AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE | BAYER IP GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |