SCHEMBL1924497

SCHEMBL1924497

O=C(O[C@H]1CN2CCC1CC2)N(Cc1ccccc1)c1cccc(Cl)c1

nearest known ligand 0.80

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 18/20 0.80
CHRM1 P11229 18/20 0.80
CHRM3 P20309 18/20 0.80
CHRM5 P08912 3/20 0.56
CHRM4 P08173 2/20 0.56
TSHR P16473 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
MAPT P10636 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19856576 0.91 CHRM3 (0.67) CHRM2CHRM1CHRM3CHRM5CHRM4
SCHEMBL1926099 0.89 CHRM2 (1.00) CHRM2CHRM1CHRM3CHRM5CHRM4
SCHEMBL1924243 0.89 CHRM2 (1.00) CHRM2CHRM1CHRM3CHRM5CHRM4
SCHEMBL2828617 0.89 CHRM2 (1.00) CHRM2CHRM1CHRM3CHRM5CHRM4
Hydrochloric Acid SCHEMBL1926555 0.88 CHRM2 (0.98) CHRM2CHRM1CHRM3CHRM5CHRM4
Hydrochloric Acid SCHEMBL1925445 0.88 CHRM2 (0.98) CHRM2CHRM1CHRM3CHRM5CHRM4
SCHEMBL15761794 0.88 CHRM3 (0.62) CHRM2CHRM1CHRM3CHRM5CHRM4
SCHEMBL1926564 0.88 CHRM2 (0.80) CHRM2CHRM1CHRM3CHRM5CHRM4
SCHEMBL5006110 0.88 CHRM2 (0.90) CHRM2CHRM1CHRM3CHRM5CHRM4
SCHEMBL1924793 0.88 CHRM2 (0.80) CHRM2CHRM1CHRM3CHRM5CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1300407-B2 CARBAMATES DERIVED FROM ARYLALKYLAMINES S A L V A T LAB SA (ES) 2011-06-08 EP claimed
EP-1300407-B2 CARBAMATES DERIVED FROM ARYLALKYLAMINES S A L V A T LAB SA (ES) 2011-06-08 EP disclosed