Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 8/20 | 0.74 |
| ▸ | DNMT3B | Q9UBC3 | 6/20 | 0.74 |
| ▸ | DOT1L | Q8TEK3 | 6/20 | 0.56 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.56 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.56 |
| ▸ | HNMT | P50135 | 2/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.56 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.56 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.56 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.56 |
| ▸ | INMT | O95050 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
| ▸ | PNMT | P11086 | 1/20 | 0.56 |
| ▸ | NNMT | P40261 | 1/20 | 0.56 |
| ▸ | WDR5 | P61964 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.56 |
| ▸ | RBBP5 | Q15291 | 1/20 | 0.56 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6341709 | 0.87 | DOT1L (0.73) | DNMT1DNMT3BDOT1LCARM1EHMT2 | |
| SCHEMBL14174632 | 0.87 | DOT1L (0.73) | DNMT1DNMT3BDOT1LCARM1EHMT2 | |
| SCHEMBL22276327 | 0.85 | DNMT1 (1.00) | DNMT1DNMT3BDOT1LCARM1EHMT2 | |
| SCHEMBL5055205 | 0.85 | DNMT1 (1.00) | DNMT1DNMT3BDOT1LCARM1EHMT2 | |
| SCHEMBL5055228 | 0.85 | DNMT1 (1.00) | DNMT1DNMT3BDOT1LCARM1EHMT2 | |
| SCHEMBL14174715 | 0.83 | DNMT1 (0.73) | DNMT1DNMT3BDOT1LCARM1EHMT2 | |
| SCHEMBL29056321 | 0.81 | NT5E (0.58) | DNMT1DNMT3BLMNANT5EHIF1A | |
| SCHEMBL3036901 | 0.79 | LMNA (0.65) | DNMT1DNMT3BLMNANT5EHIF1A | |
| SCHEMBL21132768 | 0.79 | LMNA (0.65) | DNMT1DNMT3BLMNANT5EHIF1A | |
| SCHEMBL3036906 | 0.79 | LMNA (0.65) | DNMT1DNMT3BLMNANT5EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136194-A1 | CHEMOENZYMATIC SYNTHESIS OF S-NUCLEOSYL AMINO ACIDS (SNA), ANALOGS OF S-ADENOSYL-L-METHIONINE AND S-ADENOSYL-L-HOMOCYSTEINE AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2017-08-10 | — | — | WO | disclosed |