SCHEMBL19246306

SCHEMBL19246306

O=Cc1ccccc1OCCCCCCCC(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.66
ALDH1A1 P00352 3/20 0.62
HPGD P15428 1/20 0.62
HTT P42858 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
RAD52 P43351 1/20 0.54
PPARA Q07869 3/20 0.51
LTB4R Q15722 1/20 0.49
LTB4R2 Q9NPC1 1/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7292324 1.00 PTGDR2 (0.66) PTGDR2ALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL5304037 0.93 PTGDR2 (0.70) PTGDR2ALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL2557964 0.88 PTGDR2 (0.72) PTGDR2ALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL4266947 0.87 PTGDR2 (0.50) PTGDR2ALDH1A1HPGDHTTSMN1; SMN2
SCHEMBL8163174 0.86 LMNA (0.62) ALDH1A1KMT2AMEN1PPARALTB4R
SCHEMBL8151680 0.86 LMNA (0.62) ALDH1A1KMT2AMEN1PPARALTB4R
SCHEMBL8158709 0.86 LMNA (0.62) ALDH1A1KMT2AMEN1PPARALTB4R
SCHEMBL8161670 0.86 LMNA (0.62) ALDH1A1KMT2AMEN1PPARALTB4R
SCHEMBL8162525 0.86 LMNA (0.62) ALDH1A1KMT2AMEN1PPARALTB4R
SCHEMBL8148742 0.86 LMNA (0.62) ALDH1A1KMT2AMEN1PPARALTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2409569-B1 Method for administering GLP-1 molecules EMISPHERE TECH INC (US) 2017-08-16 EP disclosed