⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266223 | 0.74 | — | — | |
| SCHEMBL4421188 | 0.70 | — | — | |
| SCHEMBL13318883 | 0.70 | — | — | |
| SCHEMBL15337447 | 0.70 | — | — | |
| SCHEMBL19443129 | 0.70 | — | — | |
| SCHEMBL263839 | 0.70 | — | — | |
| SCHEMBL1680254 | 0.70 | — | — | |
| SCHEMBL1680547 | 0.67 | — | — | |
| SCHEMBL8456025 | 0.67 | — | — | |
| SCHEMBL8473680 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439433-A | CEPHALOSPORIN ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1984-03-27 | — | — | US | claimed |
| US-4307090-A | CEPHALOSPORINS - BACTERICIDES | ROUSSEL UCLAF (FR) | 1981-12-22 | — | — | US | claimed |
| US-4287193-A | ANTIBIOTIC DERIVATIVES OF CEPHALOSPORANIC ACID | ROUSSEL UCLAF (FR) | 1981-09-01 | — | — | US | claimed |
| EP-2328412-A1 | IAP INHIBITORS | Tetralogic Pharmaceuticals Corp. (US) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010033531-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORP. (US) | 2010-03-25 | — | — | WO | disclosed |
| EP-1745041-A2 | QUINOXALINE INHIBITORS OF THE HEDGEHOG SIGNALLING PATHWAY | Genentech, Inc. (US) | 2007-01-24 | — | — | EP | disclosed |
| WO-2006078283-A2 | QUINOXALINE INHIBITORS OF HEDGEHOG SIGNALLING | GENENTECH, INC. (US) | 2006-07-27 | — | — | WO | disclosed |
| US-5159070-A | Process for the preparation of derivative of 7-[(2-hydroxyimino)-acetamido]-cephalosporanic acid | ROUSSEL UCLAF (FR) | 1992-10-27 | — | — | US | disclosed |
| US-4729990-A | PENICILLIN | FARMITALIA CARLO ERBA S.P.A. (IT) | 1988-03-08 | — | — | US | disclosed |
| US-4577016-A | DISPLACEMENT | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-03-18 | — | — | US | disclosed |
| EP-0127847-A1 | 7-Oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1984-12-12 | — | — | EP | disclosed |
| US-4439433-A | CEPHALOSPORIN ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1984-03-27 | — | — | US | disclosed |
| US-4374834-A | CEPHEM ANTIBIOTICS | Uclaf, Roussel (FR) | 1983-02-22 | — | — | US | disclosed |
| US-4325951-A | 1-Oxadethiacephalosporin derivatives and antibacterial use thereof | MEIJI SEIKA KAISHA, LTD. (JP) | 1982-04-20 | — | — | US | disclosed |
| US-4307090-A | CEPHALOSPORINS - BACTERICIDES | ROUSSEL UCLAF (FR) | 1981-12-22 | — | — | US | disclosed |
| US-4287193-A | ANTIBIOTIC DERIVATIVES OF CEPHALOSPORANIC ACID | ROUSSEL UCLAF (FR) | 1981-09-01 | — | — | US | disclosed |
| US-4259333-A | ANTIBIOTICS, BACTERICIDES | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1981-03-31 | — | — | US | disclosed |