Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 14/20 | 0.56 |
| ▸ | IDO1 | P14902 | 8/20 | 0.56 |
| ▸ | METAP2 | P50579 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16682089 | 0.80 | METAP2 (0.62) | TDO2IDO1METAP2CYP1A2 | |
| SCHEMBL15230134 | 0.76 | METAP2 (0.65) | TDO2IDO1METAP2CYP1A2 | |
| SCHEMBL26522444 | 0.75 | METAP2 (0.54) | TDO2IDO1METAP2CYP1A2 | |
| SCHEMBL24355254 | 0.75 | METAP2 (0.56) | TDO2IDO1METAP2CYP1A2 | |
| SCHEMBL14723382 | 0.75 | PTPN6 (0.66) | TDO2IDO1METAP2CYP1A2 | |
| SCHEMBL19249009 | 0.75 | METAP2 (0.56) | TDO2IDO1METAP2CYP1A2 | |
| SCHEMBL30602766 | 0.75 | PTPN6 (0.66) | TDO2IDO1METAP2CYP1A2 | |
| SCHEMBL18556930 | 0.74 | METAP2 (0.52) | TDO2IDO1METAP2CYP1A2 | |
| SCHEMBL15230661 | 0.74 | METAP2 (0.56) | TDO2IDO1METAP2CYP1A2 | |
| SCHEMBL16675979 | 0.74 | METAP2 (0.52) | TDO2IDO1METAP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133258-A1 | 1H-INDAZOLE DERIVATIVE AND USE THEREOF AS IDO INHIBITOR | 西华大学 | 2017-08-10 | — | — | WO | disclosed |