SCHEMBL19249593

SCHEMBL19249593

BrCc1cccc2c1CCCCC2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.48
BAD Q92934 1/20 0.48
TSHR P16473 2/20 0.41
TBXA2R P21731 1/20 0.39
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
DHFR P00374 2/20 0.38
LMNA P02545 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP9 P14780 1/20 0.36
MMP14 P50281 1/20 0.36
ADAM17 P78536 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8483842 0.98 BCL2L1 (0.50) BCL2L1BADTSHRTBXA2RALDH1A1
SCHEMBL30306120 0.98 BCL2L1 (0.50) BCL2L1BADTSHRTBXA2RALDH1A1
SCHEMBL10494159 0.82 PNMT (0.45) BCL2L1BADTSHRALDH1A1SMN1; SMN2
SCHEMBL3150959 0.82 BCL2L1 (0.43) BCL2L1BADTSHRTBXA2RALDH1A1
SCHEMBL9720039 0.81 BCL2L1 (0.54) BCL2L1BADTSHRTBXA2RALDH1A1
SCHEMBL5753897 0.80 BCL2L1 (0.53) BCL2L1BADTSHRTBXA2RALDH1A1
SCHEMBL10602990 0.80 PNMT (0.50) BCL2L1BADTSHRTBXA2RALDH1A1
SCHEMBL9678350 0.78 BCL2L1 (0.42) BCL2L1BADTSHRTBXA2RALDH1A1
Hydrochloric Acid SCHEMBL10647798 0.78 PNMT (0.49) BCL2L1BADTSHRTBXA2RALDH1A1
SCHEMBL10494233 0.78 PNMT (0.45) BCL2L1BADTSHRALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017132912-A1 ALKYLAMINE WITH BENZOALICYCLIC SUBSTITUENT AND APPLICATION THEREOF 华东理工大学 2017-08-10 WO disclosed