Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24782527 | 0.86 | — | — | |
| SCHEMBL19116617 | 0.85 | CRBN (0.34) | LTA4HCHRM2CHRM3GRIN1GRIN2A | |
| SCHEMBL25738952 | 0.82 | GRIN1 (0.40) | LTA4HCHRM2CHRM3GRIN1GRIN2A | |
| SCHEMBL3436929 | 0.82 | CHRM2 (0.48) | LTA4HCHRM2CHRM3GRIN1GRIN2A | |
| SCHEMBL13460109 | 0.82 | GRIN1 (0.40) | LTA4HCHRM2CHRM3GRIN1GRIN2A | |
| SCHEMBL26456980 | 0.80 | GRIN1 (0.42) | LTA4HCHRM2CHRM3GRIN1GRIN2A | |
| SCHEMBL15564387 | 0.78 | HTR2A (0.36) | LTA4HCHRM2CHRM3GRIN1GRIN2A | |
| SCHEMBL345569 | 0.77 | LTA4H (0.34) | LTA4HCHRM2CHRM3GRIN1GRIN2A | |
| SCHEMBL25476574 | 0.77 | CHRM2 (0.41) | LTA4HCHRM2CHRM3GRIN1GRIN2A | |
| SCHEMBL38662042 | 0.76 | CHRM2 (0.39) | LTA4HCHRM2CHRM3GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072240-A1 | PROLYL HYDROXYLASE DOMAIN-CONTAINING PROTEIN (PHD) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-04 | — | — | WO | disclosed |
| US-9730912-B2 | Pharmaceutical compounds | ASTEX THERAPEUTICS LIMITED (GB) | 2017-08-15 | — | — | US | disclosed |