Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 19/20 | 0.58 |
| ▸ | LOX | P28300 | 2/20 | 0.49 |
| ▸ | LOXL3 | P58215 | 2/20 | 0.49 |
| ▸ | LOXL1 | Q08397 | 2/20 | 0.49 |
| ▸ | LOXL4 | Q96JB6 | 2/20 | 0.49 |
| ▸ | DAO | P14920 | 2/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19249480 | 0.93 | LOXL2 (0.57) | LOXL2LOXLOXL3LOXL1LOXL4 | |
| SCHEMBL19249641 | 0.93 | LOXL2 (0.49) | LOXL2LOXLOXL3LOXL1LOXL4 | |
| SCHEMBL20915458 | 0.92 | LOXL2 (0.56) | LOXL2LOXLOXL3LOXL1LOXL4 | |
| SCHEMBL20915461 | 0.92 | LOXL2 (0.56) | LOXL2LOXLOXL3LOXL1LOXL4 | |
| SCHEMBL19249474 | 0.91 | LOXL2 (0.51) | LOXL2LOXLOXL3LOXL1LOXL4 | |
| SCHEMBL19249359 | 0.91 | LOXL2 (0.70) | LOXL2LOXLOXL3LOXL1LOXL4 | |
| SCHEMBL19249429 | 0.91 | LOXL2 (0.53) | LOXL2LOXLOXL3LOXL1LOXL4 | |
| Hydrochloric Acid SCHEMBL20915836 | 0.90 | LOXL2 (0.70) | LOXL2LOXLOXL3LOXL1LOXL4 | |
| Hydrochloric Acid SCHEMBL20915834 | 0.90 | LOXL2 (0.70) | LOXL2LOXLOXL3LOXL1LOXL4 | |
| Hydrochloric Acid SCHEMBL29595915 | 0.90 | LOXL2 (0.70) | LOXL2LOXLOXL3LOXL1LOXL4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136871-A1 | INDOLE AND AZAINDOLE HALOALLYLAMINE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF | PHARMAXIS LTD. (AU) | 2017-08-17 | — | — | WO | disclosed |