SCHEMBL19250170

SCHEMBL19250170

CCCn1c(-c2ccc(-c3ccc4c(C=C(C#N)C#N)cn(CCSCC)c4c3)cc2)c(C=C(C#N)C#N)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.41
KMT2A Q03164 6/20 0.41
SNCA P37840 5/20 0.41
ALDH1A1 P00352 4/20 0.39
MAPT P10636 3/20 0.39
LMNA P02545 2/20 0.39
APP P05067 5/20 0.38
PTGDR2 Q9Y5Y4 5/20 0.33
DNM2 P50570 1/20 0.33
DNM1 Q05193 1/20 0.33
KDM4E B2RXH2 2/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
THRB P10828 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CNR2 P34972 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19250166 0.80 SNCA (0.60) MEN1KMT2ASNCAALDH1A1MAPT
SCHEMBL19250165 0.77 ALDH1A1 (0.56) MEN1KMT2ASNCAALDH1A1MAPT
SCHEMBL19250171 0.76 MEN1 (0.39) MEN1KMT2ASNCAALDH1A1MAPT
SCHEMBL19250168 0.73 MEN1 (0.68) MEN1KMT2ASNCAALDH1A1MAPT
SCHEMBL19250169 0.68 MEN1 (0.61) MEN1KMT2ASNCAALDH1A1MAPT
SCHEMBL21505486 0.68 SNCA (0.63) MEN1KMT2ASNCAAPPPTGDR2
SCHEMBL21505491 0.66 SNCA (0.71) MEN1KMT2ASNCAALDH1A1MAPT
SCHEMBL21505495 0.66 ALDH1A1 (0.46) MEN1KMT2ASNCAALDH1A1MAPT
SCHEMBL23581768 0.64 ALDH1A1 (0.47) MEN1KMT2ASNCAALDH1A1MAPT
SCHEMBL27383475 0.64 ALDH1A1 (0.46) MEN1KMT2ASNCAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170235032-A1 OPTICAL FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-17 US disclosed