Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22752561 | 0.90 | CNR2 (0.38) | CNR2CNR1 | |
| SCHEMBL19251280 | 0.88 | CNR2 (0.38) | CNR2CNR1 | |
| SCHEMBL18935708 | 0.88 | AR (0.39) | CNR2CNR1 | |
| SCHEMBL28897627 | 0.77 | AR (0.44) | — | |
| SCHEMBL22778697 | 0.75 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL19135617 | 0.75 | CNR2 (0.46) | CNR2CNR1 | |
| SCHEMBL2739660 | 0.73 | KIF11 (0.44) | — | |
| SCHEMBL19251045 | 0.73 | CNR2 (0.49) | CNR2CNR1 | |
| SCHEMBL19251082 | 0.73 | CNR2 (0.49) | CNR2CNR1 | |
| SCHEMBL22778802 | 0.72 | CNR2 (0.48) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732083-B2 | Tricyclic gyrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-08-15 | — | — | US | disclosed |