Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.32 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251390 | 0.90 | PIK3R1 (0.38) | PIK3CDPIK3R1PIK3CGPIK3CAPIK3CB | |
| SCHEMBL19251405 | 0.85 | PIK3CD (0.39) | PIK3CDPIK3R1PIK3CGPIK3CAPIK3CB | |
| SCHEMBL19251423 | 0.81 | PIK3CD (0.50) | PIK3CDPIK3R1PIK3CGPIK3CAPIK3CB | |
| SCHEMBL19251386 | 0.79 | PIK3CD (0.47) | PIK3CDPIK3R1PIK3CGPIK3CAPIK3CB | |
| SCHEMBL19251397 | 0.78 | PIK3CD (0.51) | PIK3CDPIK3R1PIK3CGPIK3CAPIK3CB | |
| SCHEMBL19251396 | 0.77 | PIK3CD (0.45) | PIK3CDPIK3R1PIK3CGPIK3CAPIK3CB | |
| SCHEMBL19251398 | 0.74 | PIK3CD (0.48) | PIK3CDPIK3R1PIK3CGPIK3CAPIK3CB | |
| SCHEMBL19251404 | 0.72 | PIK3CD (0.49) | PIK3CDPIK3R1PIK3CGPIK3CAPIK3CB | |
| SCHEMBL19251631 | 0.72 | PIK3R1 (0.60) | PIK3CDPIK3R1PIK3CGPIK3CAPIK3CB | |
| SCHEMBL19072474 | 0.71 | PIK3CD (0.45) | PIK3CDPIK3R1PIK3CGPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |