Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 13/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.32 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251385 | 0.90 | PIK3CD (0.39) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251396 | 0.88 | PIK3CD (0.45) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251398 | 0.84 | PIK3CD (0.48) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251404 | 0.83 | PIK3CD (0.49) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251631 | 0.80 | PIK3R1 (0.60) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251611 | 0.78 | PIK3CD (0.44) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252623 | 0.78 | PIK3CD (0.44) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251401 | 0.77 | PIK3CD (0.49) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252621 | 0.77 | PIK3R1 (0.49) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251629 | 0.77 | PIK3R1 (0.49) | PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |