Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251396 | 0.81 | PIK3CD (0.45) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251474 | 0.80 | PIK3CD (0.33) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251628 | 0.77 | PIK3R1 (0.56) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251398 | 0.74 | PIK3CD (0.48) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251404 | 0.73 | PIK3CD (0.49) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251401 | 0.72 | PIK3CD (0.49) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19252623 | 0.72 | PIK3CD (0.44) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251611 | 0.72 | PIK3CD (0.44) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251388 | 0.71 | PIK3R1 (0.47) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19251390 | 0.70 | PIK3R1 (0.38) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |