Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251258 | 0.71 | MEN1 (0.32) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL21416997 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL1264882 | 0.68 | KCNH2 (0.45) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL256203 | 0.67 | ALDH1A1 (0.64) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL29377581 | 0.67 | ALDH1A1 (0.64) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL11400597 | 0.65 | ALDH1A1 (0.61) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8878556 | 0.65 | ALDH1A1 (0.61) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL31296371 | 0.65 | ALDH1A1 (0.61) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL297275 | 0.64 | ALDH1A1 (0.59) | ALDH1A1MAPTGAAKMT2AMEN1 | |
| SCHEMBL2288703 | 0.64 | ALDH1A1 (0.59) | ALDH1A1MAPTGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10472342-B2 | Compounds and compositions for inhibition of FASN | FORMA THERAPEUTICS, INC. (US) | 2019-11-12 | — | — | US | disclosed |
| US-9732083-B2 | Tricyclic gyrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10472342-B2 | Compounds and compositions for inhibition of FASN | FASN, FABP1, SCD | ALDH1A1 1393/4885MAPT 3053/4885GAA 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.