Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.40 |
| ▸ | PI4KA | P42356 | 3/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251466 | 0.85 | PIK3CD (0.52) | ADORA2AADORA2BADORA1PIK3CDPIK3R1 | |
| SCHEMBL19251609 | 0.84 | PIK3CD (0.41) | ADORA2AADORA2BADORA1PIK3CDPIK3R1 | |
| SCHEMBL19251475 | 0.81 | PIK3CD (0.61) | ADORA2AADORA2BADORA1PIK3CDPIK3R1 | |
| SCHEMBL19251476 | 0.75 | PIK3CD (0.53) | ADORA2AADORA2BADORA1PIK3CDPIK3R1 | |
| SCHEMBL19251465 | 0.74 | PIK3CD (0.64) | ADORA2AADORA2BADORA1PIK3CDPIK3R1 | |
| SCHEMBL19251462 | 0.71 | PIK3CD (0.65) | ADORA2AADORA2BADORA1PIK3CDPIK3R1 | |
| SCHEMBL13269043 | 0.67 | ADORA2A (0.62) | ADORA2AADORA2BADORA1PIK3CDPI4KA | |
| SCHEMBL11862452 | 0.67 | PI4KB (0.69) | ADORA2AADORA2BADORA1PIK3CDPI4KA | |
| SCHEMBL13268709 | 0.67 | ADORA2A (0.62) | ADORA2AADORA2BADORA1PIK3CDPI4KA | |
| SCHEMBL19251468 | 0.67 | PIK3CD (0.63) | ADORA2AADORA2BADORA1PIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |