Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 15/20 | 0.69 |
| ▸ | PI4KA | P42356 | 14/20 | 0.69 |
| ▸ | PI4K2B | Q8TCG2 | 14/20 | 0.69 |
| ▸ | PI4K2A | Q9BTU6 | 14/20 | 0.69 |
| ▸ | EGFR | P00533 | 3/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | HCK | P08631 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.44 |
| ▸ | PRKDC | P78527 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27422663 | 0.88 | PI4KA (0.64) | PI4KBPI4KAPI4K2BPI4K2AEGFR | |
| SCHEMBL11829935 | 0.84 | PI4KA (0.48) | PI4KBPI4KAPI4K2BPI4K2AEGFR | |
| SCHEMBL18292155 | 0.82 | PI4KA (1.00) | PI4KBPI4KAPI4K2BPI4K2AEGFR | |
| SCHEMBL11813800 | 0.79 | PI4KA (0.62) | PI4KBPI4KAPI4K2BPI4K2AEGFR | |
| SCHEMBL6354390 | 0.78 | PI4KA (0.69) | PI4KBPI4KAPI4K2BPI4K2AEGFR | |
| SCHEMBL11842210 | 0.77 | MAPT (0.46) | PI4KBPI4KAPI4K2BPI4K2AADORA2A | |
| SCHEMBL21638051 | 0.77 | PI4KA (0.72) | PI4KBPI4KAPI4K2BPI4K2AEGFR | |
| SCHEMBL3538512 | 0.76 | PI4KA (0.77) | PI4KBPI4KAPI4K2BPI4K2AEGFR | |
| SCHEMBL11862441 | 0.75 | ADORA2A (0.60) | PI4KBPI4KAPI4K2BPI4K2AADORA2A | |
| SCHEMBL17815604 | 0.75 | XDH (0.41) | PI4KBPI4KAPI4K2BPI4K2ASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3936454-A | ANTIANGINAL, BRONCHODILATOR | WARNER-LAMBERT COMPANY (US) | 1976-02-03 | — | — | US | disclosed |