SCHEMBL1925209

SCHEMBL1925209

CC(C)[C@H](N)C(=O)O[C@H](C)[C@H](N)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.58
SLC1A3 P43003 2/20 0.40
SLC1A2 P43004 2/20 0.40
SLC1A1 P43005 2/20 0.40
CASR P41180 1/20 0.36
TP53 P04637 1/20 0.36
ACHE P22303 1/20 0.35
P2RY10 O00398 2/20 0.33
GPR174 Q9BXC1 2/20 0.33
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
SLC15A1 P46059 1/20 0.33
NR1I2 O75469 1/20 0.32
PTGS1 P23219 1/20 0.32
ADRA1A P35348 1/20 0.32
LMNA P02545 1/20 0.32
BLM P54132 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Serine SCHEMBL10612187 0.88 SLC7A5 (0.45) SLC7A5SLC1A3SLC1A2SLC1A1CASR
Isoleucine SCHEMBL1899454 0.88 SLC7A5 (0.45) SLC7A5SLC1A3SLC1A2SLC1A1ACHE
SCHEMBL2702062 0.87 SLC7A5 (0.46) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL288383 0.85 SLC7A5 (0.44) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL8988392 0.85 SLC1A3 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL9118329 0.85 SLC1A3 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL6038226 0.85 SLC7A5 (0.44) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL18050156 0.85 SLC7A5 (0.44) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL23286474 0.84 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL1514131 0.84 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0210257-A4 PROTEIN WHICH IS CHARACTERISTIC OF RHEUMATOID ARTHRITIS. HURWITZ CHARLES (US) 1988-01-20 EP claimed
EP-0210257-A1 PROTEIN WHICH IS CHARACTERISTIC OF RHEUMATOID ARTHRITIS HURWITZ, Charles (US) 1987-02-04 EP claimed
WO-1986004588-A1 PROTEIN WHICH IS CHARACTERISTIC OF RHEUMATOID ARTHRITIS HURWITZ CHARLES (US) 1986-08-14 WO claimed
CN-118308092-A Eu3+/Tb3+Fluorescent sensor for preparing amino acid by doping protein eutectic, method and application 青岛大学 2024-07-09 CN disclosed
US-RE49583-E1 Inducible expression systems TET SYSTEMS GMBH & CO. KG (DE) 2023-07-18 US disclosed
CN-112469729-A Analgesic and method of use 悉尼大学 2021-03-09 CN disclosed
US-20190117840-A1 TISSUE SCAFFOLDS Northwick Park Institute for Medical Research Ltd. (GB) 2019-04-25 US disclosed
EP-3439709-A1 TISSUE SCAFFOLDS Northwick Park Institute For Medical Research Ltd (GB) 2019-02-13 EP disclosed
WO-2017174965-A1 TISSUE SCAFFOLDS NORTHWICK PARK INSTITUTE FOR MEDICAL RESEARCH LTD RESEARCH LTD (GB) 2017-10-12 WO disclosed
EP-2802661-A1 MUTATED CEPHALOSPORIN HYDROXYLASE AND ITS APPLICATION IN DEACETYLCEPHALOSPORANIC ACID SYNTHESIS Orchid Chemicals and Pharmaceuticals Ltd (IN) 2014-11-19 EP disclosed
CN-101304758-B Recombinant interferon Alpha2 (IFNAlpha2) mutants YEDA RES & DEV 2013-08-21 CN disclosed
EP-1989221-A2 NOVEL LIPASES AND USES THEREOF DSMIP Assets B.V. (NL) 2008-11-12 EP disclosed
EP-1954811-A2 INDUCIBLE EXPRESSION SYSTEMS Academisch Medisch Centrum (NL) 2008-08-13 EP disclosed
WO-2007096201-A2 NOVEL UPASES AND USES THEREOF DSM IP ASSETS B.V. (NL) 2007-08-30 WO disclosed
WO-2007058527-A2 INDUCIBLE EXPRESSION SYSTEMS ACADEMISCH MEDISCH CENTRUM (NL) 2007-05-24 WO disclosed
US-6428624-B1 MIXTURE OF REDUCING SUGAR AND BASE CATALYST; MIXTURE ENRICHED IN AT LEAST ONE AMINO ACID OF SERINE, THREONINE, VALINE, LEUCINE AND ISOLEUCINE R. J. REYNOLDS TOBACCO CO. 2002-08-06 US disclosed
US-20020074008-A1 Method of providing flavorful and aromatic compounds JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2002-06-20 US disclosed
CN-1034416-Y With comfortable kinin antagonists for the preparation method of peptide He toru spa 1997-04-02 CN disclosed
CN-1131561-A Macrostem onion active extract DUAN CHANGXIANG (CN) 1996-09-25 CN disclosed
WO-1996003158-A1 USE OF LOW MOLECULAR WEIGHT AMINO ACIDS IN OPHTHALMIC COMPOSITIONS ALCON LABORATORIES, INC. (US) 1996-02-08 WO disclosed