SCHEMBL6038226

SCHEMBL6038226

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nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.44
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
CASR P41180 1/20 0.35
TP53 P04637 1/20 0.35
P2RY10 O00398 2/20 0.33
GPR174 Q9BXC1 2/20 0.33
USP2 O75604 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288383 1.00 SLC7A5 (0.44) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL18050156 1.00 SLC7A5 (0.44) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL2702062 0.98 SLC7A5 (0.46) SLC7A5SLC1A3SLC1A2SLC1A1CASR
Threonine SCHEMBL16982372 0.88 SLC7A5 (0.41) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL8988392 0.88 SLC1A3 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL9118329 0.88 SLC1A3 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL1925209 0.85 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL23286474 0.83 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL1811512 0.83 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL1514131 0.83 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2SLC1A1CASR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060281897-A1 Potentialization of the activation of high molecular weight prodrugs DIATOS S.A. (FR) 2006-12-14 US disclosed
EP-1701743-A2 POTENTIATION OF THE ACTIVATION OF HIGH-MOLECULAR-MASS PRODRUGS Diatos (FR) 2006-09-20 EP disclosed
WO-2005021043-A2 HIGH-MOLECULAR-MASS PRODRUGS DIATOS (FR) 2005-03-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060281897-A1 Potentialization of the activation of high molecular weight prodrugs CD44, MMP12, FOLH1 SLC7A5 523/4885SLC1A3 2811/4885SLC1A2 2536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.