Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1689401 | 0.86 | HDAC6 (0.37) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL3187773 | 0.84 | HDAC6 (0.36) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL7023795 | 0.82 | CA14 (0.39) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL14789144 | 0.82 | HDAC6 (0.35) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL1926409 | 0.80 | HDAC6 (0.36) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL14311330 | 0.79 | CA12 (0.38) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL5001089 | 0.79 | CA12 (0.55) | HDAC6HDAC1HDAC2CA12CA1 | |
| SCHEMBL1949583 | 0.79 | CA12 (0.34) | HDAC6HDAC1HDAC2CTSLCTSB | |
| SCHEMBL15487077 | 0.78 | CA12 (0.37) | HDAC6HDAC1HDAC2CTSDCTSL | |
| SCHEMBL992004 | 0.78 | CA12 (0.37) | HDAC6HDAC1HDAC2CTSDCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011071951-A2 | N-ACYLOXYSULFONAMIDE AND N-HYDROXY-N-ACYLSULFONAMIDE DERIVATIVES | JOHNS HOPKINS UNIVERSITY (US) | 2011-06-16 | — | — | WO | disclosed |