SCHEMBL19252720

SCHEMBL19252720

CCC(C)Oc1ccccc1C=CC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.55
KDM4E B2RXH2 2/20 0.52
PTGER1 P34995 2/20 0.52
PTGER4 P35408 2/20 0.52
PTGER3 P43115 2/20 0.52
PTGER2 P43116 2/20 0.52
GAA P10253 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.51
NFE2L2 Q16236 2/20 0.48
TFEB P19484 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
NFKB1 P19838 1/20 0.46
CA4 P22748 1/20 0.46
LMNA P02545 4/20 0.46
MAPT P10636 3/20 0.46
PLA2G1B P04054 1/20 0.46
ATG4B Q9Y4P1 1/20 0.46
NPC1 O15118 1/20 0.46
BCHE P06276 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5160514 1.00 HTT (0.55) HTTKDM4EPTGER1PTGER4PTGER3
SCHEMBL5175460 0.88 HTT (0.58) HTTKDM4EPTGER1PTGER4PTGER3
SCHEMBL19244241 0.86 KDM4E (0.51) HTTKDM4ESMN1; SMN2NFE2L2TFEB
SCHEMBL19244261 0.86 NFE2L2 (0.52) KDM4ESMN1; SMN2NFE2L2TFEBLMNA
SCHEMBL19244240 0.86 KDM4E (0.51) HTTKDM4ESMN1; SMN2NFE2L2TFEB
SCHEMBL19244263 0.86 NFE2L2 (0.52) KDM4ESMN1; SMN2NFE2L2TFEBLMNA
SCHEMBL11683164 0.85 HTT (0.55) HTTKDM4EPTGER1PTGER4PTGER3
SCHEMBL19244308 0.85 KDM4E (0.48) KDM4ESMN1; SMN2NFE2L2TFEBCA1
SCHEMBL19244322 0.85 KDM4E (0.47) HTTKDM4ESMN1; SMN2NFE2L2TFEB
SCHEMBL19244309 0.85 KDM4E (0.48) KDM4ESMN1; SMN2NFE2L2TFEBCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10126478-B2 Resin composition and optical compensation film using same TOSOH CORPORATION (JP) 2018-11-13 US disclosed
US-20170242174-A1 RESIN COMPOSITION AND OPTICAL COMPENSATION FILM USING SAME TOSOH CORPORATION (JP) 2017-08-24 US disclosed