Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107635 | 0.92 | POLB (0.36) | TDP1POLBAPEX1HTT | |
| SCHEMBL8397404 | 0.91 | TDP1 (0.37) | TDP1POLBAPEX1HTTNPC1 | |
| SCHEMBL30602832 | 0.90 | POLB (0.36) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL29399137 | 0.90 | POLB (0.39) | TDP1POLBAPEX1HTTNPC1 | |
| SCHEMBL292630 | 0.90 | POLB (0.39) | TDP1POLBAPEX1HTTNPC1 | |
| SCHEMBL554511 | 0.90 | POLB (0.36) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL13384918 | 0.89 | POLB (0.36) | TDP1POLBAPEX1HTT | |
| SCHEMBL30887119 | 0.89 | POLB (0.36) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL15385236 | 0.88 | POLB (0.35) | TDP1POLBAPEX1HTTPPARG | |
| SCHEMBL13021489 | 0.88 | POLB (0.35) | TDP1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023228055-A1 | UV/HEVL-FILTERING CONTACT LENSES | ALCON INC. (CH) | 2023-11-30 | — | — | WO | claimed |
| US-20230374306-A1 | UV/HEVL-FILTERING CONTACT LENSES | ALCON INC. (CH) | 2023-11-23 | — | — | US | claimed |
| EP-3928967-B1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2023-07-26 | — | — | EP | claimed |
| EP-3743270-B1 | CAST-MOLDING PROCESS FOR PRODUCING UV-ABSORBING CONTACT LENSES | ALCON INC (CH) | 2022-06-08 | — | — | EP | claimed |
| EP-3634733-B1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2021-07-21 | — | — | EP | claimed |
| EP-3634732-B1 | METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES | ALCON RES LTD (US) | 2021-07-21 | — | — | EP | claimed |
| US-20180354214-A1 | METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2018-12-13 | — | — | US | claimed |
| US-20180355112-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2018-12-13 | — | — | US | claimed |
| CN-117716262-A | Method for producing wettable silicone hydrogel contact lenses | 爱尔康公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117492230-A | Zhou Pao and month polishing gradient contact lens | 爱尔康公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117492228-A | Zhou Pao and month polishing gradient contact lens | 爱尔康公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117492229-A | Zhou Pao and month polishing gradient contact lens | 爱尔康公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117492231-A | Zhou Pao and month polishing gradient contact lens | 爱尔康公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117492232-A | Zhou Pao and month polishing gradient contact lens | 爱尔康公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-115298574-A | Embedded silicone hydrogel contact lenses | 爱尔康公司 | 2022-11-04 | — | — | CN | disclosed |
| US-11001647-B2 | Soft silicone medical devices | ALCON INC. (CH) | 2021-05-11 | — | — | US | disclosed |
| US-20190177444-A1 | SOFT SILICONE MEDICAL DEVICES | ALCON INC. (CH) | 2019-06-13 | — | — | US | disclosed |
| US-10253112-B2 | Soft silicone medical devices | NOVARTIS AG (CH) | 2019-04-09 | — | — | US | disclosed |
| EP-3420384-A1 | SOFT SILICONE MEDICAL DEVICES | Novartis AG (CH) | 2019-01-02 | — | — | EP | disclosed |
| US-20170240658-A1 | SOFT SILICONE MEDICAL DEVICES | ALCON INC. (CH) | 2017-08-24 | — | — | US | disclosed |