Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29613654 | 0.95 | NPC1 (0.35) | TDP1POLBAPEX1HTTNPC1 | |
| SCHEMBL373843 | 0.95 | NPC1 (0.35) | TDP1POLBAPEX1HTTNPC1 | |
| SCHEMBL19252768 | 0.91 | TDP1 (0.39) | TDP1POLBAPEX1HTTNPC1 | |
| SCHEMBL29399137 | 0.90 | POLB (0.39) | TDP1POLBAPEX1HTTNPC1 | |
| SCHEMBL554511 | 0.90 | POLB (0.36) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL292630 | 0.90 | POLB (0.39) | TDP1POLBAPEX1HTTNPC1 | |
| SCHEMBL30602832 | 0.90 | POLB (0.36) | TDP1POLBAPEX1HTTALDH1A1 | |
| SCHEMBL13384918 | 0.89 | POLB (0.36) | TDP1POLBAPEX1HTT | |
| SCHEMBL15385236 | 0.89 | POLB (0.35) | TDP1POLBAPEX1HTT | |
| SCHEMBL13021489 | 0.89 | POLB (0.35) | TDP1POLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0488145-B1 | Ultraviolet light absorbing intraocular lens | MENICON CO LTD (JP) | 1999-06-09 | — | — | EP | claimed |
| EP-0488145-A2 | Ultraviolet light absorbing ocular lens | Menicon Co., Ltd. (JP) | 1992-06-03 | — | — | EP | claimed |
| EP-0488145-B1 | Ultraviolet light absorbing intraocular lens | MENICON CO LTD (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0488145-A2 | Ultraviolet light absorbing ocular lens | Menicon Co., Ltd. (JP) | 1992-06-03 | — | — | EP | disclosed |