Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | BLM | P54132 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | HTR1A | P08908 | 2/20 | 0.63 |
| ▸ | HTR2A | P28223 | 2/20 | 0.63 |
| ▸ | HTR2C | P28335 | 2/20 | 0.63 |
| ▸ | HTR2B | P41595 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.63 |
| ▸ | HTR7 | P34969 | 1/20 | 0.63 |
| ▸ | MTOR | P42345 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3043368 | 1.00 | NPSR1 (0.63) | NPSR1ALDH1A1BLMKDM4ENFKB1 | |
| SCHEMBL27717518 | 0.95 | BLM (0.58) | NPSR1ALDH1A1BLMKDM4ENFKB1 | |
| SCHEMBL3078225 | 0.95 | BLM (0.58) | NPSR1ALDH1A1BLMKDM4ENFKB1 | |
| SCHEMBL27717526 | 0.90 | GAA (0.54) | NPSR1ALDH1A1BLMKDM4ENFKB1 | |
| SCHEMBL3046095 | 0.90 | GAA (0.54) | NPSR1ALDH1A1BLMKDM4ENFKB1 | |
| SCHEMBL6728790 | 0.90 | ALOX15 (0.57) | NPSR1ALDH1A1BLMKDM4ENFKB1 | |
| SCHEMBL6728788 | 0.90 | ALOX15 (0.57) | NPSR1ALDH1A1BLMKDM4ENFKB1 | |
| SCHEMBL10974835 | 0.89 | ALOX15 (0.73) | NPSR1ALDH1A1BLMKDM4ENFKB1 | |
| SCHEMBL10974832 | 0.89 | ALOX15 (0.73) | NPSR1ALDH1A1BLMKDM4ENFKB1 | |
| SCHEMBL23501891 | 0.88 | NPSR1 (0.60) | NPSR1ALDH1A1BLMKDM4ENFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113788780-A | Synthesis method of N-acetyl-5-methoxytryptamine | 河北维达康生物科技有限公司 | 2021-12-14 | — | — | CN | disclosed |
| US-20200246465-A1 | USE OF TRYPTOPHAN DERIVATIVES FOR PROTEIN FORMULATIONS | GENENTECH, INC. (US) | 2020-08-06 | — | — | US | disclosed |
| CN-110916891-A | Intelligent cold therapy spectrum control system, control method and cold therapy equipment | 王龙 | 2020-03-27 | — | — | CN | disclosed |
| US-20170239355-A1 | USE OF TRYPTOPHAN DERIVATIVES FOR PROTEIN FORMULATIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2017-08-24 | — | — | US | disclosed |
| CN-101855218-A | Synthesizing of deuterated catechol and benzo [d] [1,3] dioxole and derivative thereof | CONCERT PHARMACEUTICALS INC | 2010-10-06 | — | — | CN | disclosed |
| CN-101273024-A | Novel benzo[D][1,3]-dioxol derivatives | CONCERT PHARMACEUTICALS INC (US) | 2008-09-24 | — | — | CN | disclosed |