SCHEMBL19253225

SCHEMBL19253225

Nc1c(N)c(-c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.46
MAPT P10636 3/20 0.46
LMNA P02545 2/20 0.46
HTT P42858 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
CYP3A4 P08684 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
ALDH1A1 P00352 4/20 0.44
MAPK1 P28482 3/20 0.41
NPSR1 Q6W5P4 1/20 0.41
KDM4E B2RXH2 2/20 0.41
HPGD P15428 2/20 0.41
GLA P06280 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KMT2A Q03164 2/20 0.40
BRD4 O60885 1/20 0.40
TDO2 P48775 1/20 0.40
MAOA P21397 1/20 0.40
AKT2 P31751 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2069055 0.97 HSD17B10 (0.48) HSD17B10MAPTLMNAHTTTDP1
SCHEMBL6228506 0.91 HSD17B10 (0.48) HSD17B10MAPTLMNAHTTTDP1
SCHEMBL5030574 0.91 HSD17B10 (0.48) HSD17B10MAPTLMNAHTTTDP1
SCHEMBL25632271 0.88 HSD17B10 (0.46) HSD17B10MAPTLMNAHTTTDP1
SCHEMBL1899394 0.88 HSD17B10 (0.46) HSD17B10MAPTLMNAHTTTDP1
SCHEMBL20837496 0.88 ALDH1A1 (0.50) HSD17B10MAPTLMNAHTTTDP1
SCHEMBL675595 0.88 ALDH1A1 (0.50) HSD17B10MAPTLMNAHTTTDP1
Hydrochloric Acid SCHEMBL10927721 0.85 HSD17B10 (0.48) HSD17B10MAPTLMNAHTTTDP1
SCHEMBL25011930 0.83 AKT2 (0.47) HSD17B10MAPTLMNAHTTTDP1
SCHEMBL573405 0.83 ALDH1A1 (0.50) HSD17B10MAPTLMNAHTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250026889-A1 TWO DIMENSIONAL POLYMERS COMPRISED OF A COMBINATION OF STIFF AND COMPLIANT MOLECULAR UNITS U.S. GOVERNMENT, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2025-01-23 US disclosed
US-12110367-B2 Two-dimensional polymers comprised of a combination of stiff and compliant molecular units THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2024-10-08 US disclosed
CN-118165204-A Sub-chemical covalent organic framework material for producing hydrogen peroxide by photocatalysis and preparation method thereof 江南大学 2024-06-11 CN disclosed
US-20200148827-A1 TWO-DIMENSIONAL POLYMERS COMPRISED OF A COMBINATION OF STIFF AND COMPLIANT MOLECULAR UNITS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2020-05-14 US disclosed
US-10590241-B2 Two-dimensional polymers comprised of a combination of stiff and compliant molecular units THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2020-03-17 US disclosed
US-20170240706-A1 TWO-DIMENSIONAL POLYMERS COMPRISED OF A COMBINATION OF STIFF AND COMPLIANT MOLECULAR UNITS ARMY, UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE 2017-08-24 US disclosed