Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26104675 | 0.88 | MEN1 (0.30) | MEN1MAPTHTTKMT2ASMN1; SMN2 | |
| SCHEMBL996026 | 0.85 | CA12 (0.41) | MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL668901 | 0.85 | CA12 (0.41) | MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9938547 | 0.81 | KDM4E (0.40) | MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9938274 | 0.81 | ELANE (0.38) | SMN1; SMN2 | |
| SCHEMBL9938614 | 0.81 | MEN1 (0.42) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL23199797 | 0.81 | CA2 (0.34) | MEN1KMT2A | |
| SCHEMBL669403 | 0.81 | KMT2A (0.55) | MEN1MAPTKMT2A | |
| SCHEMBL14644345 | 0.80 | KMT2A (0.39) | NCEH1MEN1MAPTHTTKMT2A | |
| Hydrochloric Acid SCHEMBL23199782 | 0.79 | ESR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017535-B2 | Amphiphilic compounds with neuroprotective properties | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2018-07-10 | — | — | US | disclosed |
| US-20170240588-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) | 2017-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240588-A1 | AMPHIPHILIC COMPOUNDS WITH NEUROPROTECTIVE PROPERTIES | GAP43, GRIN2A, GRIN3A | NCEH1 921/4885MEN1 4065/4885MAPT 153/4885 |
| US-10017535-B2 | Amphiphilic compounds with neuroprotective properties | GAP43, GRIN2A, GRIN3A | NCEH1 921/4885MEN1 4065/4885MAPT 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.