⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723 | 0.96 | — | — | |
| SCHEMBL19206133 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL3697304 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL66739 | 0.92 | — | — | |
| Trimethylammonium SCHEMBL14244281 | 0.92 | DNM1 (0.50) | — | |
| Bromide SCHEMBL2584826 | 0.92 | — | — | |
| Iodide SCHEMBL6387501 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL15322639 | 0.92 | — | — | |
| SCHEMBL11621000 | 0.92 | — | — | |
| Arsenic SCHEMBL5237643 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3419982-B1 | NEW STABLE SILYLATING REAGENTS | CALIFORNIA INST OF TECHN (US) | 2023-11-15 | — | — | EP | disclosed |
| US-20210323983-A1 | STABLE SILYLATING REAGENTS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2021-10-21 | — | — | US | disclosed |
| US-11028107-B2 | Stable silylating reagents | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2021-06-08 | — | — | US | disclosed |
| EP-3419982-A1 | NEW STABLE SILYLATING REAGENTS | California Institute of Technology (US) | 2019-01-02 | — | — | EP | disclosed |
| WO-2017147110-A1 | NEW STABLE SILYLATING REAGENTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-08-31 | — | — | WO | disclosed |
| US-20170240571-A1 | STABLE SILYLATING REAGENTS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2017-08-24 | — | — | US | disclosed |